Undesirable effects may be reduced by using the minimum effective dose for the shortest possible duration. Concomitant long term use of NSAIDs long term, should undergo regular medical supervision to monitor for adverse events. Avoid contact with eyes and mucus membrane. The total dose of product should not exceed 25g daily. If there is no improvement or the condition is aggravated, the doctor should be consulted. Although the systemic effects should be low, the drug should be used with caution in patients with renal, cardiac or hepatic impairment, history of peptic ulceration, inflammatory bowel disease or bleeding diathesis. Elderly patients are particularly susceptible to the adverse effects of NSAIDs. Prolonged use of NSAIDs in the elderly is not recommended. Where prolonged therapy is required, patients should be reviewed regularly. As NSAIDs can interfere with platelet function, they should be used with caution in patients with intracranial haemorrhage and bleeding diathesis. It should only be used on non-diseased skin. To avoid the possibility of photosensitivity, patients should be advised against excessive exposure to sunlight of treated areas. This medicine contains 300 mg of alcohol (ethanol) in each 1 g. which is equivalent to 300 mg/g (30%w/w). It may cause burning sensation on damaged skin.
