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ব্যবহার

Aluminium Chloride Hexahydrate topical solution is indicated for the treatment of hyperhidrosis of the armpits (axillae), the hands and the feet.

ফার্মাকোলজি

Aluminium Chloride Hexahydrate acts locally in the stratum corneum and terminal duct to relieve hyperhidrosis. Aluminium salts cause an obstruction of the ducts of sweat glands at the skin surface. It seems that the metal (Aluminium) ions precipitate with mucopolysaccharides, damaging epithelial cells along with the duct lumen and forms a plug (gel) that blocks sweat output.

সেবনবিধি

This topical solution is for application to the axillae, palms of the hands or soles of the feet. Before applying Aluminium Chloride Hexahydrate, the affected area should be dried thoroughly to avoid burning of the skin. Apply this topical solution at night after drying the affected areas carefully. Wash off in the morning. Do not re-apply the product during the day. Initially the product may be applied each night until sweating stops during the day. The frequency of application may then be reduced to twice a week or less.

পার্শ্বপ্রতিক্রিয়া

Aluminium Chloride Hexahydrate may cause irritation which may be alleviated by the use of a weak corticosteroid cream.Skin and Subcutaneous Tissue Disorders: Very common: Application site irritation.Immune System Disorders: Not known: Application site hypersensitivity including application site dermatitis.Skin and Subcutaneous Tissue Disorders: Not known: Application site reactions including pain, pruritus, erythema, rash and skin burning sensation.

সতর্কতা

Aluminium Chloride Hexahydrate reacts with water to produce Hydrochloric acid. Therefore the areas to be treated should be completely dry before application to avoid skin burning. Application should be restricted to the affected area(s) only. Aluminium Chloride Hexahydrate should not be applied to skin that has been shaved within 12 hours or which is broken or irritated. Hair removal products should not be used on areas to be treated within 12 hours before or after applying Aluminium Chloride Hexahydrate. Avoid contact with eyes, nostrils, mouth or other mucous membranes. In case of accidental contact with the eyes or other mucous membranes, rinse well with water. Avoid direct contact with clothing, jewellery and polished metal surfaces.

গর্ভাবস্থায় ও স্তন্যদানকালে ব্যবহার

Pregnancy: There are no data from the use of topical Aluminium Chloride Hexahydrate in pregnant women. Studies in animals have shown reproductive toxicity following oral and parenteral administration. Due to the nature of aluminium it is unlikely that it penetrates the skin, therefore no effects during pregnancy are anticipated with use of Aluminium Chloride Hexahydrate solution.Lactation: It is unknown whether topical Aluminium Chloride Hexahydrate is excreted in human milk. Due to the nature of aluminium, it is unlikely that it penetrates the skin, therefore no effects on the breast-fed newborn/infant are anticipated with use of Aluminium Chloride Hexahydrate solution. If Aluminium Chloride Hexahydrate is used during breast-feeding, care should be taken not to get any solution on the breasts to ensure that the baby is not accidentally exposed to Aluminium Chloride Hexahydrate. If any of the solution does get on the breasts, the patient should be instructed to wash-off all traces before beginning breast-feeding.

মাত্রাতিরিক্ত ব্যবহার

Application more frequently than recommended may increase the severity of skin irritation. Ingestion can cause nausea, vomiting, diarrhoea and burning in the mouth and throat. Systemic absorption of this should be considered a possibility in the event of overdosage.

সংরক্ষণ

Store in a cool and dry place, protected from light. Store below 25°C temperature. Keep away from naked flame. Store upright.

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